Ehud Lamm

The genome as a developmental organ


Ehud Lamm, The genome as a developmental organ. In Journal of Physiology 592 (11):2237-2244 (2014), 2014

Keywords: Development,ENCODE,Epigenetics,Epigenetic Inheritance,Evo-Devo,Evolvability,Gene,Genome,History,Inheritance Systems,Junk DNA

DOI: 10.1113/jphysiol.2014.271734

Abstract:

This paper applies the conceptual toolkit of Evolutionary Developmental Biology (evo‐devo) to the evolution of the genome and the role of the genome in organism development. This challenges both the Modern Evolutionary Synthesis, the dominant view in evolutionary theory for much of the 20th century, and the typically unreflective analysis of heredity by evo‐devo. First, the history of the marginalization of applying system‐thinking to the genome is described. Next, the suggested framework is presented. Finally, its application to the evolution of genome modularity, the evolution of induced mutations, the junk DNA versus ENCODE debate, the role of drift in genome evolution, and the relationship between genome dynamics and symbiosis with microorganisms are briefly discussed.
  • Home
  • Research
  • By topic
    • Chromosome
    • Co-Evolution
    • Cultural Evolution
    • Development
    • ENCODE
    • Epigenetics
    • Epigenetic inheritance
    • Essays
    • Evo-Devo
    • Evolution of Language
    • Evolvability
    • Gene
    • Genome
    • History
    • Holobionts
    • Individuality
    • Inheritance Systems
    • Mechanisms
    • Metaphors
    • Modeling
    • Normativity
    • Book Reviews
  • Books
    • Landscapes of Collectivity in the Life Sciences
    • Biological Computation
    • The Living Genome
  • Talks
  • Teaching
  • Odyssey '15
  • Odyssey Question
  • Reading Groups
  • Lab
    • Conceptual Biology Lab
    • Lab People
  • Stuff
  • News
     

Hand coded site. Powered by yst. Generated on 2023-07-04.